Can a Nutritional Supplement Extend the Life of Botox?

by Dean Anderson

zytaze extend botox

A full decade has passed since the FDA approved Botox for cosmetic use, and one Houston area doctor has a timely anniversary present for the popular muscle paralyzer. Oculoplastic surgeon and biochemist Dr. Charles Soparkar has developed a supplement called Zytaze which he claims can extend the wrinkle-fighting effects of Botox injections up to 30%. According to his studies, Botox effectiveness is closely linked to zinc levels in tissue, and Zytaze contains the exact kind of zinc to prime the body for botulinum toxin treatments. News of Zytaze’s unique effect is stirring interest and excitement in the cosmetic, scientific, and medical communities.

The botulinum toxin in dermal injectables like Botox, Dysport, and Xeomin helps smooth facial features due to its ability to disrupt communication between nerves and muscle tissue. Thus, when injected into a person’s brow or cheek, it relaxes local muscles responsible for wrinkles. Botulinum toxin chains are all zinc-dependent metalloproteases, meaning without zinc they either won’t work or their effects will be muted. With this fact in mind Dr. Soparkar began speculating that extra zinc to the patients’ diet prior to the injections could affect the longevity of Botox treatments.

Dr. Soparkar developed pills with high levels of zinc citrate and phytase, an enzyme rich in phosphorous which is crucial to zinc absorption, and dubbed the mixture Zytaze. He then ran double-blind placebo-controlled trials of the concoction on a group of 44 patients at The Methodist Hospital in Houston to test his hypothesis. The patients were to take the supplement twice a day during the four days leading up to the injection and two the morning of. Those who took Zytaze experienced an average 23.6% increase in the duration of Botox effects, with some patients experiencing a 30% boost.

While millions get Botox for cosmetic purposes, thousands more need the injections to regulate conditions such as uncontrollable eye spasms, upper limb spasticity, and cervical dystonia. The use of Zytaze could mean that these people can regulate their debilitating conditions in fewer treatments. The usual 3-4 month break between clinic visits for medical patients and cosmetic Botox users alike could stretch to 5-6 months, potentially saving thousands of dollars over the course of years.

The discovery of zinc’s Botox boosting effect also has scientists speculating about its role in cases of full or partial botulinum toxin resistance. Although zinc is common in foods such as chicken, beef, eggs, and beans, many commonly digested nutrients and foods actually hinder zinc absorption including iron, calcium, magnesium, alcohol, and “phytates,” antioxidant compounds found in whole grains, nuts and legumes. Doctors estimate up to 50% of people are zinc deficient, many of which are people 65 years or older, a demographic that also responded poorly to Botox during initial FDA trials. The incorporation of Zytaze into more Botox therapies could re-open the treatment to many who were excluded before.

While Zytaze was developed using established scientific principles and rigorous testing, doctors are still learning how the supplement interacts with Botox. Curiously, fitness fanatics who’ve tried Zytaze typically report lessened effects, perhaps because they metabolize the supplement’s nutrients faster than those with less active lifestyles. Until scientists fully understand its effects, Zytaze is being offered by prescription only at the price of $60-$80 for a ten-pill pack.

If you’re interested in learning more about Zytaze or the effects of Botox treatments, contact us today! Our Healthy Skin Portal representatives can book you a personal consult with a skincare specialist near you.

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